IGF-1 Antibody

• Description :

  This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

• Specifications :

  Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 1-4 µg/mL, In-vitro neutralization of biological activity of IGF-1 (order BSA/sodium azide-free format)

• UniProt :

  P05019

• Host :

  Mouse

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  IGF1/1020

• Applications :

  FACS, IF, Neutralization

• Purity :

  Protein G affinity chromatography

• Format :

  Purified

• Buffer :

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution :

  Store the IGF-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations :

  This IGF-1 antibody is available for research use only.

• Storage Conditions :

  Store the IGF-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation :

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes :

  Optimal dilution of the IGF-1 antibody should be determined by the researcher.

• CAS Number :

  9007-83-4

• Location :

  Cytoplasmic (secreted)