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IGF-1 Antibody

CAT: 0800-V2616-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V2616-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 1-4 µg/mL, In-vitro neutralization of biological activity of IGF-1 (order BSA/sodium azide-free format)
UniProt
P05019
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
IGF1/1020
Applications
FACS, IF, Neutralization
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the IGF-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This IGF-1 antibody is available for research use only.
Storage Conditions
Store the IGF-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the IGF-1 antibody should be determined by the researcher.
Location
Cytoplasmic (secreted)
Product Datasheet
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