TOX3 Antibody

CAT: 0800-V2541-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0800-V2541-20UGSize:20 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG) -box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB) . TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL
UniProt
O15405
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment (139 amino acid residues around aa 200-400) from the human protein was used as the immunogen for the TOX3 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
TOX3/1123
Applications
WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the TOX3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TOX3 antibody is available for research use only.
Storage Conditions
Store the TOX3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the TOX3 antibody should be determined by the researcher.
Location
Cytoplasmic & nuclear
Image Legend
Western blot testing of human A431 cell lysate with TOX3 antibody. Predicted molecular weight ~63 kDa.

Related Products

CatalogName
RQ7024TOX Antibody
RQ7554TOX2 Antibody / GCX-1
V2542SAF-100UGTOX-3 Antibody
F54408-0.08MLTOX-3 Antibody
V2542-20UGTOX-3 Antibody
F54408-0.4MLTOX-3 Antibody
V2542-100UGTOX-3 Antibody
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.05MLAntibody
F53954-0.2MLAntibody

Alternative Products

CatalogName
33-370TOX3 Antibody [TOX3/1123]
61-675TOX3 Antibody
NBP2-45165-0.1mgMouse Monoclonal TOX3 Antibody (TOX3/1123)
NBP2-45166-0.1mgMouse Monoclonal TOX3 Antibody (TOX3/1124)
NBP2-47749BMouse Monoclonal TOX3 Antibody (TOX3/1124) [Biotin]
NBP2-47748BMouse Monoclonal TOX3 Antibody (TOX3/1123) [Biotin]
NBP2-47749HMouse Monoclonal TOX3 Antibody (TOX3/1124) [HRP]
NBP2-47748FMouse Monoclonal TOX3 Antibody (TOX3/1123) [FITC]
NBP2-47749FMouse Monoclonal TOX3 Antibody (TOX3/1124) [FITC]
NBP2-47748HMouse Monoclonal TOX3 Antibody (TOX3/1123) [HRP]

Popular Products