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Alpha Fetoprotein Antibody

CAT: 0800-V2479SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V2479SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop) . This mAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P02771
Host
Mouse
Reactivity
Human, Mouse
Immunogen
AFP purified from serum of a hepatoma patient was used as the immunogen for the Alpha Fetoprotein antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
C2
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the Alpha Fetoprotein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Alpha Fetoprotein antibody is available for research use only.
Storage Conditions
Store the Alpha Fetoprotein antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human fetal liver stained with Alpha Fetoprotein antibody (C2) .

UniProtKB · P02771

Alpha-fetoprotein

FETA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02771
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AFP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RBU3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CopperMetal-bindingNickel

PTM

Disulfide bondGlycoproteinPhosphoproteinSulfation

Domain

RepeatSignal

Cellular component

Secreted

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Alternative Products

CatalogName
GTR17856808Alpha-Fetoprotein Antibody
GWB-C60D62Alpha Fetoprotein Antibody
F4100-03PFetoprotein, Alpha (alpha Fetoprotein, Alpha, alpha-Fetoprotein, Alpha, alpha-1-Fetoprotein, Alpha, Afp, alpha-Fetoglobulin)
F4100-03RFetoprotein, Alpha (alpha Fetoprotein, Alpha, alpha-Fetoprotein, Alpha, alpha-1-Fetoprotein, Alpha, Afp, alpha-Fetoglobulin) (FITC)
136093Fetoprotein, Alpha (Alpha-fetoprotein, AFP, Alpha-1-fetoprotein, HPAFP)

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