AFP Antibody (Alpha Fetoprotein)

AFP Antibody (Alpha Fetoprotein)

• Description: Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
• CAS Number: 9007-83-4
• UniProt: P02771
• Host: Rabbit
• Immunogen: A portion of amino acids 300-329 from the human protein was used as the immunogen for this AFP antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: WB, IHC, ELISA
• Format: Antigen affinity purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the AFP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This AFP antibody is available for research use only.