CD146 Antibody / MCAM / MUC18

• Description:

  The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. MUC18 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. MUC18 / CD146 is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

• Host:

  Mouse

• Immunogen:

  Recombinant human protein was used as the immunogen for this MUC18 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Applications:

  FACS, IF

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Store the MUC18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This MUC18 antibody is available for research use only.

• CAS Number:

  9007-83-4