CD8A Antibody
CAT:
800-V2043SAF-100UG
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CD8A Antibody
- Description: CD8 is a cell surface receptor expressed either as a heterodimer with the beta chain or as a homodimer. A majority of thymocytes and a subpopulation of mature Tcells and NK cells express CD8a. It binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in Tcell development and activation of mature Tcells. For mature Tcells, CD8 and 4 are mutually exclusive, so antibody to CD8 is generally used in conjunction with antibody to CD4. CD8a antibody is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral Tcell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+/CD8-, and in T-lymphoblastic lymphoma/leukemia, they are often co-expressed. It is also found in littoral cell angioma of the spleen.
- CAS Number: 9007-83-4
- UniProt: P01732
- Host: Mouse
- Immunogen: Human recombinant protein was used as the immunogen for this CD8a antibody.
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Applications: IHC-P, IF
- Format: Purified
- Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
- Reconstitution: Store the CD8a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
- Limitations: This CD8a antibody is available for research use only.