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NLRP7 Antibody

CAT: 0800-RQ6892Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6892Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q8WX94
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids M1-L169) was used as the immunogen for the NLRP7 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the NLRP7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This NLRP7 antibody is available for research use only.
Storage Conditions
After reconstitution, the NLRP7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NLRP7 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human splenic rupture tissue with NLRP7 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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