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NLRP3 Antibody

CAT: 0800-F51203-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F51203-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
Q96P20
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 65-91 from the human protein was used as the immunogen for this NLRP3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the NLRP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NLRP3 antibody is available for research use only.
Storage Conditions
Aliquot the NLRP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NLRP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of NLRP3 antibody and MDA-MB231 lysate. Predicted molecular weight ~118kDa.

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