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ADAM9 Antibody

CAT: 0800-RQ6596Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6596Size:100 µg
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Description
Disintegrin and metalloproteinase domain-containing protein 9 is an enzyme that in humans is encoded by the ADAM9 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q13443
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids R212-D247) was used as the immunogen for the ADAM9 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the ADAM9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ADAM9 antibody is available for research use only.
Storage Conditions
After reconstitution, the ADAM9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ADAM9 antibody should be determined by the researcher.
Location
Secreted, Cytoplasm (ER)
Image Legend
Immunofluorescent staining of FFPE human U-2 OS cells with ADAM9 antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · Q13443

Disintegrin and metalloproteinase domain-containing protein 9

ADAM9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13443
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADAM9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ADAM 9
EC number
3.4.24.-
Processing
Precursor
Secondary accessions
B7ZLN7, Q10718, Q8NFM6
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

Disease

Cone-rod dystrophy

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

Technical term

Proteomics identificationReference proteome

Domain

SignalTransmembraneTransmembrane helix
Product Datasheet
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