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LSM8 Antibody

CAT: 0800-RQ6586Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6586Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
U6 snRNA-associated Sm-like protein LSm8 is a protein that in humans is encoded by the LSM8 gene. This gene encodes a member of the like-Sm family of proteins. The encoded protein consists of a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. This protein partners with six paralogs to form a heteroheptameric ring which transiently binds U6 small nuclear RNAs and is involved in the general maturation of RNA in the nucleus.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
O95777
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human protein (amino acids M1-H96) was used as the immunogen for the LSM8 antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
6B11
Applications
WB, IHC-P, IF, FACS
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the LSM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This LSM8 antibody is available for research use only.
Storage Conditions
After reconstitution, the LSM8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the LSM8 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Immunofluorescent staining of FFPE human HeLa cells with LSM8 antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · O95777

U6 snRNA-associated Sm-like protein LSm8

LSM8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95777
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LSM8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Biological process

mRNA processingmRNA splicing

Cellular component

NucleusSpliceosome

Molecular function

RibonucleoproteinRNA-binding

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