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CD39 Antibody / ENTPD1

CAT: 0800-RQ6480Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6480Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ectonucleoside triphosphate diphosphohydrolase-1 (gene: ENTPD1; protein: NTPDase1) also known as CD39 (Cluster of Differentiation 39), is a typical cell surface enzyme with a catalytic site on the extracellular face. The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P49961
Host
Rabbit
Reactivity
Human
Immunogen
An E. coli-derived human protein (amino acids H79-E411) was used as the immunogen for the CD39 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CD39 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CD39 antibody is available for research use only.
Storage Conditions
After reconstitution, the CD39 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CD39 antibody should be determined by the researcher.
Image Legend
Immunofluorescent staining of FFPE human colon cancer with CD39 antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · P49961

Ectonucleoside triphosphate diphosphohydrolase 1

ENTP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49961
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ENTPD1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.1.5
Processing
—
Secondary accessions
A9Z1X8, B4DWB9, B4E1X1, B7Z599, G3XAF6, Q5T561, Q5T562, Q86VV3, Q9UQQ9, Q9Y3Q9
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingCalciumGTP-bindingMagnesiumNucleotide-binding

Technical term

Direct protein sequencingProteomics identificationReference proteome

Disease

Disease variantHereditary spastic paraplegiaNeurodegeneration

PTM

Disulfide bondGlycoproteinLipoproteinPalmitate

Molecular function

Hydrolase

Cellular component

Membrane

Domain

TransmembraneTransmembrane helix

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