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Elovl4 Antibody

CAT: 0800-RQ6478Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6478Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Elongation of very long chain fatty acids protein 4 is a protein that in humans is encoded by the ELOVL4 gene. This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9EQC4
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
An E. coli-derived mouse protein (amino acids M1-E312) was used as the immunogen for the Elovl4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Elovl4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Elovl4 antibody is available for research use only.
Storage Conditions
After reconstitution, the Elovl4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Elovl4 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of FFPE mouse RM-1 cells with Elovl4 antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · Q9EQC4

Very long chain fatty acid elongase 4

ELOV4_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9EQC4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Elovl4
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
2.3.1.199
Processing
—
Secondary accessions
Q8JZV3
Protein keywords

Cellular component

Endoplasmic reticulumMembrane

Biological process

Fatty acid biosynthesisFatty acid metabolismLipid biosynthesisLipid metabolism

PTM

Glycoprotein

Technical term

Reference proteome

Molecular function

Transferase

Domain

TransmembraneTransmembrane helix

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