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KCNJ8 Antibody

CAT: 0800-RQ6193Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6193Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Potassium inwardly-rectifying channel, subfamily J, member 8, also known as KCNJ8, is a human gene encoding the Kir6.1 protein. Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS) .
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q15842
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A human recombinant partial protein (amino acids M1-S424) was used as the immunogen for the KCNJ8 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the KCNJ8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This KCNJ8 antibody is available for research use only.
Storage Conditions
After reconstitution, the KCNJ8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the KCNJ8 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human pancreatic cancer with KCNJ8 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · Q15842

ATP-sensitive inward rectifier potassium channel 8

KCNJ8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15842
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KCNJ8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
O00657
Protein keywords

Disease

Disease variant

Molecular function

Ion channelVoltage-gated channel

Biological process

Ion transportPotassium transportTransport

Cellular component

Membrane

PTM

Phosphoprotein

Ligand

Potassium

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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