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Nectin 3 Antibody

CAT: 0800-RQ5996Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5996Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nectin-3, also known as poliovirus receptor-related 3, is a 95 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. It is mapped to 3q13.13. This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9NQS3
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids E92-N296) was used as the immunogen for the Nectin 3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Nectin 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Nectin 3 antibody is available for research use only.
Storage Conditions
After reconstitution, the Nectin 3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Nectin 3 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human rectal cancer with Nectin 3 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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