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TRPV2 Antibody / VRL1

CAT: 0800-RQ5848Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5848Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TRPV2 (Transient Receptor Potential Cation Channel Subfamily V Member 2), also known as VRL1, is a protein that, in humans, is encoded by the TRPV1 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52?C. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is though that in other tissues the channel may be activated by stimuli other than heat.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9Y5S1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human protein (amino acids S7-K390) was used as the immunogen for the TRPV2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the TRPV2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TRPV2 antibody is available for research use only.
Storage Conditions
After reconstitution, the TRPV2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TRPV2 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human A549, 2) human A431, 3) rat brain, 4) mouse brain, 5) mouse heart and 6) mouse lung lysate with TRPV2 antibody. Expected molecular weight: 85-95 kDa depending on glycosylation level.

UniProtKB · Q9Y5S1

Transient receptor potential cation channel subfamily V member 2

TRPV2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y5S1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TRPV2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TrpV2
EC number
—
Processing
—
Secondary accessions
A6NML2, A8K0Z0, Q9Y670
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Domain

ANK repeatRepeatTransmembraneTransmembrane helix

Ligand

Calcium

Molecular function

Calcium channelIon channel

Biological process

Calcium transportIon transportTransport

Cellular component

Cell membraneCytoplasmMembrane

PTM

GlycoproteinPhosphoprotein

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