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TRPV3 Antibody

CAT: 0800-R31084Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31084Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transient Receptor Potential Cation Channel Subfamily V Member 3, also known as VRL3, is encoded by the TRPV3 gene. The protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. Peier et al. (2002) localized the gene to a BAC clone mapped to chromosome 17p13. They mapped the mouse gene to chromosome 11B4. Peier et al. (2002) stably expressed mouse Trpv3 in Chinese hamster ovary cells and assayed electrophysiologic activity by whole cell voltage-clamp techniques. They determined that it is a cation-permeable channel activated by warm and hot temperatures. Xu et al. (2002) showed that increasing temperature from approximately 22 to 40 degrees Celsius in mammalian cells transfected with human TRPV3 elevated intracellular calcium by activating a nonselective cationic conductance.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q8NET8
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids (757-773 RRTDFNKIQDSSRNNSK-human) were used as the immunogen for this TRPV3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the TRPV3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TRPV3 antibody is available for research use only.
Storage Conditions
After reconstitution, the TRPV3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the TRPV3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of TRPV3 antibody and Lane 1: HeLa; 2: A549; 3: MCF-7 cell lysate. Predicted/observed size ~90KD

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