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Monkey NOD1 Antibody / CARD4

CAT: 0800-RQ5831Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5831Size:100 µg
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Description
Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. NOD1 is a member of NOD-like receptor protein family and is a close relative of NOD2. NOD1 is mapped to 7p14.3. It recognizes bacterial molecules and stimulates an immune reaction. NOD1 protein contains a caspase recruitment domain (CARD) . This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. What wore, it has been shown that NOD1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q9Y239
Host
Rabbit
Reactivity
Monkey
Immunogen
Amino acids NQTLKHLWLIQNQITAK were used as the immunogen for the Monkey NOD1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Monkey NOD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Monkey NOD1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Monkey NOD1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Monkey NOD1 antibody should be determined by the researcher.
Image Legend
Western blot testing of monkey 1) heart and 2) skeletal muscle with Monkey NOD1 antibody. Predicted molecular weight: ~107 kDa.

UniProtKB · Q9Y239

Nucleotide-binding oligomerization domain-containing protein 1

NOD1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y239
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOD1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hNod1
EC number
—
Processing
—
Secondary accessions
B4DTU3, Q549U4, Q8IWF5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisImmunityInnate immunity

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembrane

Domain

Leucine-rich repeatRepeat

PTM

LipoproteinPalmitateUbl conjugation

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