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HOXD11 Antibody

CAT: 0800-RQ5818Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5818Size:100 µg
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Description
Homeobox protein Hox-D11 is a protein that in humans is encoded by the HOXD11 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Flow cytyometry: 1-3ug/million cells, Immunofluorescence: 2-4 µg/mL
UniProt
P31277
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids VREVAFRDYGLERAKWPYR from the human protein were used as the immunogen for the HOXD11 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the HOXD11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This HOXD11 antibody is available for research use only.
Storage Conditions
After reconstitution, the HOXD11 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the HOXD11 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE human testis cancer with HOXD11 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · P31277

Homeobox protein Hox-D11

HXD11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31277
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HOXD11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NIS4, Q9NS02
Protein keywords

Molecular function

Developmental proteinDNA-binding

Domain

Homeobox

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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