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Thioredoxin 2 Antibody

CAT: 0800-RQ5560Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5560Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. It is mapped to 22q12.3. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
CAS Number
9007-83-4
Specifications
Western blot: 0.25-0.5 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Immunofluorescence: 2-4 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q99757
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A human recombinant protein (amino acids T60-G166) was used as the immunogen for the Thioredoxin 2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Thioredoxin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Thioredoxin 2 antibody is available for research use only.
Storage Conditions
After reconstitution, the Thioredoxin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Thioredoxin 2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HeLa, 2) K562, 3) ThP-1, 4) U-2 OS and 5) U-87 MG cell lysate with Thioredoxin 2 antibody. Predicted molecular weight ~13 kDa.

UniProtKB · Q99757

Thioredoxin, mitochondrial

THIOM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99757
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TXN2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MTRX, Mt-Trx
EC number
—
Processing
Precursor
Secondary accessions
Q5JZA0, Q6FH60, Q9UH29
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bond

Biological process

Electron transportTransport

Cellular component

Mitochondrion

Disease

NeurodegenerationPrimary mitochondrial disease

Domain

Redox-active centerTransit peptide

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