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SMURF2 Antibody

CAT: 0800-RQ5537Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5537Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. The SMURF2 gene is mapped to chromosome 17q22-q23 based on sequence similarity between the SMURF2 sequence and a genomic contig. SMURF2 is a HECT domain E3 ubiquitin ligase involved in degradation of SMADs, TGF-beta receptor (TGFBR), and other substrates. It also functions in regulation of neuronal and planar cell polarity, induction of senescence, and tumor suppression.
CAS Number
9007-83-4
Specifications
Western blot: 0.25-0.5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9HAU4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A human recombinant protein (amino acids W303-Q387) was used as the immunogen for the SMURF2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the SMURF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SMURF2 antibody is available for research use only.
Storage Conditions
After reconstitution, the SMURF2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SMURF2 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat testis, 2) rat pancreas, 3) rat stomach, 4) mouse testis and 5) mouse pancreas lysate with SMURF2 antibody. Predicted molecular weight ~86 kDa.

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