Products for Research Use Only
RegisterLogin

NQO1 Antibody

CAT: 0800-R31977Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31977Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. And this FAD-binding protein forms homodimers and reduces quinones to hydroquinones. In addition, this protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
P15559
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids EVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK of human NQO1 were used as the immunogen for the NQO1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the NQO1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This NQO1 antibody is available for research use only.
Storage Conditions
After reconstitution, the NQO1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NQO1 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat liver, 2) rat lung, 3) human HeLa, 4) A549, 5) MM231, 6) SW620 and 7) 22RV1 with NQO1 antibody. Predicted/observed molecular weight ~30 kDa.

UniProtKB · P15559

NAD(P)H dehydrogenase [quinone] 1

NQO1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15559
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NQO1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.6.5.2
Processing
—
Secondary accessions
B2R5Y9, B4DNM7, B7ZAD1, Q86UK1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Ligand

FADFlavoproteinNADNADP

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Molecular function

Oxidoreductase

Related Products

CatalogName
RQ8297NQO2 Antibody
F51241-0.4MLNQO2 Antibody
RQ5463NQO2 Antibody
F51241-0.08MLNQO2 Antibody
RQ4624NONO Antibody / p54nrb Antibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
F53954-0.2MLAntibody
F53954-0.05MLAntibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody

Alternative Products

CatalogName
70R-18946NQO1 antibody

Popular Products