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NQO1 Antibody

CAT: 0800-F50335-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F50335-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NQO1 is a member of the NAD (P) H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) .
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50
UniProt
P15559
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 118-144 from the human protein was used as the immunogen for this NQO1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, IF, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the NQO1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NQO1 antibody is available for research use only.
Storage Conditions
Aliquot the NQO1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NQO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of NQO1 antibody and NCI-H460 lysate. Predicted molecular weight ~30kDa.

UniProtKB · P15559

NAD(P)H dehydrogenase [quinone] 1

NQO1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15559
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NQO1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.6.5.2
Processing
—
Secondary accessions
B2R5Y9, B4DNM7, B7ZAD1, Q86UK1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Ligand

FADFlavoproteinNADNADP

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Molecular function

Oxidoreductase

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