Histone H2AX Recombinant Antibody / H2AFX

Histone H2AX Recombinant Antibody / H2AFX

• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [RefSeq]
• CAS Number: 9000-83-3
• UniProt: P16104
• Host: Rabbit
• Immunogen: A synthetic peptide specific to human Histone H2A.X / H2AFX was used as the immunogen for the H2AFX antibody.
• Clonality: Monoclonal
• Isotype: IgG
• Type: Recombinant
• Applications: IHC-P, WB
• Format: Purified
• Buffer: Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
• Reconstitution: Store the H2AFX antibody at -20oC.
• Limitations: This H2AFX antibody is available for research use only.