CD3e Antibody

• Description:

  The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [RefSeq]

• Specifications:

  Immunohistochemistry (FFPE) : 1:50-1:200

• UniProt:

  P07766

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  A synthetic peptide specific to mouse CD3 epsilon / CD3E was used as the immunogen for the CD3e antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  COB-3

• Type:

  Recombinant

• Applications:

  IHC-P

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the CD3e antibody at -20oC.

• Limitations:

  This CD3e antibody is available for research use only.

• Storage Conditions:

  Store the CD3e antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the CD3e antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Image Legend:

  IHC staining of FFPE mouse spleen tissue with CD3e antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.