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IL-34 Antibody

CAT: 0800-RQ4931Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4931Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin 34 (IL-34) is a protein belonging to a group of cytokines called interleukins. It was originally identified in humans, by large scale screening of secreted proteins; chimpanzee, murine, rat and chicken interleukin 34 orthologs have also been found. The protein is composed of 241 amino acids, 39 kilodaltons in mass, and forms homodimers. IL-34 increases growth or survival of immune cells known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. This gene is mapped to 16q22.1.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q6ZMJ4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids NEPLEMWPLTQNEECTVTGFLRDKLQYR from the human protein were used as the immunogen for the IL-34 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the IL-34 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IL-34 antibody is available for research use only.
Storage Conditions
After reconstitution, the IL-34 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the IL-34 antibody should be determined by the researcher.
Location
Secreted
Image Legend
Western blot testing of 1) human placenta, 2) rat brain and 3) mouse brain lysate with IL-34 antibody at 0.5ug/ml. Predicted molecular weight ~26 kDa, secreted as an ~39 kDa homodimer that may be glycosylated.

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