SLIT2 Antibody

• Description:

  Slit homolog 2 protein is thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. [UniProt]

• Specifications:

  Western blot: 1:500-1:2000

• UniProt:

  O94813

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide specific to human SLIT2 was used as the immunogen for the SLIT2 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  ACGF-19

• Type:

  Recombinant

• Applications:

  WB

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the SLIT2 antibody at -20oC.

• Limitations:

  This SLIT2 antibody is available for research use only.

• Storage Conditions:

  Store the SLIT2 antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the SLIT2 antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Image Legend:

  Western blot testing of human SH-SY5Y cell lysate with SLIT2 antibody. Expected molecular weight: ~180-210 kDa (full length), ~140 kDa (N-terminal fragment), 55-60 kDa (C-terminal fragment) .