JAK2 Antibody

• Description:

  Tyrosine-protein kinase JAK2 is a non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO) ; or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. [UniProt]

• Specifications:

  Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence/Immunocytochemistry: 1:50-1:200

• UniProt:

  O60674

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide specific to human JAK2 was used as the immunogen for the JAK2 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  COG-10

• Type:

  Recombinant

• Applications:

  IF/ICC, IHC-P, WB

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the JAK2 antibody at -20oC.

• Limitations:

  This JAK2 antibody is available for research use only.

• Storage Conditions:

  Store the JAK2 antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the JAK2 antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Location:

  Nuclear, cytoplasmic

• Image Legend:

  Immunofluorescent staining of FFPE human A549 cells with JAK2 antibody (green) and Beta Tubulin antibody (red) . HIER: steam section in pH6 citrate buffer for 20 min.