JAK2 Antibody

• Description:

  JAK2 is a non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO) ; or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. [UniProt]

• Specifications:

  Western blot: 1:500

• UniProt:

  O60674

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This JAK2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 834-868 amino acids from the C-terminal region of human JAK2.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the JAK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This JAK2 antibody is available for research use only.

• Storage Conditions:

  Aliquot the JAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the JAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Mouse, Rat, Pig, Chicken

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of lysate from LNCaP cell line using JAK2 antibody diluted at 1:1000. Predicted molecular weight ~130 kDa