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JAK2 Antibody

CAT: 0800-RQ4762Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4762Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tyrosine-protein kinase JAK2 is a non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO) ; or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. [UniProt]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence/Immunocytochemistry: 1:50-1:200
UniProt
O60674
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide specific to human JAK2 was used as the immunogen for the JAK2 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
COG-10
Type
Recombinant
Applications
IF/ICC, IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the JAK2 antibody at -20oC.
Limitations
This JAK2 antibody is available for research use only.
Storage Conditions
Store the JAK2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the JAK2 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
Immunofluorescent staining of FFPE human A549 cells with JAK2 antibody (green) and Beta Tubulin antibody (red) . HIER: steam section in pH6 citrate buffer for 20 min.

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