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XPB Antibody

CAT: 0800-RQ4567Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4567Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XPB (xeroderma pigmentosum type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex. This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL (human recombinant protein)
UniProt
P19447
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids Q665-K715 from the human protein were used as the immunogen for the XPB antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the XPB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This XPB antibody is available for research use only.
Storage Conditions
After reconstitution, the XPB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the XPB antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat testis and 2) mouse testis lysate with XPB antibody at 0.5ug/ml. Predicted molecular weight ~89 kDa.

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