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CUL2 Antibody / Cullin 2

CAT: 0800-RQ4558Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4558Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cullin 2 (CUL2) is a protein that in humans is encoded by the CUL2 gene. Using immunofluorescence, it is showed that CUL2 is a cytosolic protein that can be translocated to the nucleus by VHL. By fluorescence in situ hybridization, this gene is mapped to 10p11.2-p11.1, a region reported to show loss of heterozygosity (LOH) in several forms of human cancer, including non-clear cell renal cell carcinoma. CUL2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL (recombinant human protein)
UniProt
Q13617
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids E389-A745 from the human protein were used as the immunogen for the CUL2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CUL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CUL2 antibody is available for research use only.
Storage Conditions
After reconstitution, the CUL2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CUL2 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human K562, 2) rat brain and 3) mouse brain lysate with CUL2 antibody at 0.5ug/ml. Predicted molecular weight: ~87 kDa.
Product Datasheet
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