Products for Research Use Only
RegisterLogin

GSTM1 Antibody

CAT: 0800-RQ4483Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ4483Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S-transferase. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-4 µg/mL, Flow Cytometry: 1-3ug/1x10^6 cells
UniProt
P09488
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids EEEKIRVDILENQTMDNHMQLGMICYNPEFEKLK were used as the immunogen for the GSTM1 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
11F2
Applications
FACS, IHC-P, WB
Purity
Protein G affinity
Format
Purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the GSTM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This GSTM1 antibody is available for research use only.
Storage Conditions
After reconstitution, the GSTM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the GSTM1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Western blot testing of 1) human HeLa, 2) human T-47D, 3) rat brain, 4) rat lung, 5) rat stomach, 6) mouse lung, 7) mouse stomach and 8) mouse kidney lysate with GSTM1 antibody at 0.5ug/ml. Predicted molecular weight ~26 kDa.

Related Products

CatalogName
V7281-20UGGSTM3 Antibody
R34395-100UGGSTO1 Antibody
V7416-20UGGSTM2 Antibody
V7281SAF-100UGGSTM3 Antibody
RQ4127GSTM3 Antibody
V7281IHC-7MLGSTM3 Antibody
V7416-100UGGSTM2 Antibody
F54405-0.08MLGSTO1 Antibody
V7281-100UGGSTM3 Antibody
V7416SAF-100UGGSTM2 Antibody

Alternative Products

CatalogName
10R-10423GSTM1 antibody

Popular Products