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Cd134 Antibody / Ox40

CAT: 0800-RQ4380Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4380Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tumor necrosis factor receptor superfamily, member 4, also known as ACT35 or CD134, is a cell surface glycoprotein that was discovered through the production of a monoclonal antibody raised against the HUT-102 cell line. It belongs to the tumor necrosis factor receptor superfamily. CD134 was mapped to 1p36 by fluorescence in situ hybridization. It is the primary receptor for feline immunodeficiency virus. And CD134 expression can promote viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL (rat recombinant protein)
UniProt
P15725
Host
Rabbit
Reactivity
Rat
Immunogen
A recombinant rat protein corresponding to amino acids V20-L198 was used as the immunogen for the Cd134 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Cd134 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cd134 antibody is available for research use only.
Storage Conditions
After reconstitution, the Cd134 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Cd134 antibody should be determined by the researcher.
Location
Cytoplasm, membrane
Image Legend
Western blot testing of rat heart lysate with Cd134 antibody at 0.5ug/ml. Expected molecular weight: 29-50 kDa depending on glcyosylation level.

UniProtKB · P15725

Tumor necrosis factor receptor superfamily member 4

TNR4_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
P15725
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Tnfrsf4
Protein existence
2: Evidence at transcript level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

PTM

Disulfide bondGlycoprotein

Cellular component

Membrane

Molecular function

Receptor

Technical term

Reference proteome

Domain

RepeatSignalTransmembraneTransmembrane helix

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