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RPGR Antibody

CAT: 0800-RQ4374Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4374Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP) . Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q92834
Host
Rabbit
Reactivity
Rat
Immunogen
A recombinant human protein corresponding to amino acids A13-F338 was used as the immunogen for the RPGR antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the RPGR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RPGR antibody is available for research use only.
Storage Conditions
After reconstitution, the RPGR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the RPGR antibody should be determined by the researcher.
Prediction Reactivity
Human
Location
Cytoplasm, cytoskeleton
Image Legend
Western blot testing of rat 1) liver, 2) kidney, 3) brain and 4) heart lysate with RPGR antibody at 0.5ug/ml. Predicted molecular weight ~113 kDa.

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