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CTR1 Antibody / Copper transporter 1

CAT: 0800-RQ4345Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4345Size:100 µg
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Description
High affinity copper uptake protein 1 (Ctr1) is a protein that in humans is encoded by the SLC31A1 gene. This gene is maped to 9q32. The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
O15431
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids NGTILMETHKTVGQQMLSFPHLLQTVLHIIQ were used as the immunogen for the CTR1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the CTR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CTR1 antibody is available for research use only.
Storage Conditions
After reconstitution, the CTR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CTR1 antibody should be determined by the researcher.
Location
Cell membrane
Image Legend
Western blot testing of human 1) HepG2 and 2) PANC-1 cell lysate with CTR1 antibody at 0.5ug/ml. Expected molecular weight ~25 kDa (unmodified), 35-37 kDa (glycosylated) .

UniProtKB · O15431

High affinity copper uptake protein 1

COPT1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15431
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC31A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K8Z6, Q53GR5, Q5T1M4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneEndosomeMembrane

Ligand

Copper

Biological process

Copper transportIon transportTransport

PTM

Disulfide bondGlycoproteinOxidationPhosphoprotein

Disease

EpilepsyNeurodegeneration

Domain

TransmembraneTransmembrane helix

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