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PIAS3 Antibody

CAT: 0800-RQ4115Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4115Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
E3 SUMO-protein ligase PIAS3 is an enzyme that in humans is encoded by the PIAS3 gene. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription) ] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier) -E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL
UniProt
Q9Y6X2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids QRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRF from the human protein were used as the immunogen for the PIAS3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the PIAS3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PIAS3 antibody is available for research use only.
Storage Conditions
After reconstitution, the PIAS3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PIAS3 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HeLa, 2) U-87 MG, 3) COLO320, 4) HepG2, 5) rat brain and 6) mouse NIH3T3 lysate with PIAS3 antibody at 0.5ug/ml. Predicted molecular weight ~68 kDa.

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