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IL17A Antibody

CAT: 0800-RQ4021Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4021Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, ELISA (Capture) : 0.1-0.5 µg/mL
UniProt
Q62386
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant mouse partial protein corresponding to amino acids A26-A158 was used as the immunogen for the IL17A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the IL17A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IL17A antibody is available for research use only.
Storage Conditions
After reconstitution, the IL17A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the IL17A antibody should be determined by the researcher.
Location
Secreted, cytoplasmic
Image Legend
IHC testing of FFPE mouse spleen tissue with IL17A antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
Product Datasheet
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