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ETV6 Antibody / Tel

CAT: 0800-RQ4018Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4018Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcription factor ETV6 is a protein that in humans is encoded by the ETV6 gene. This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P41212
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant human partial protein corresponding to amino acids E327-Q448 was used as the immunogen for the ETV6 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the ETV6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ETV6 antibody is available for research use only.
Storage Conditions
After reconstitution, the ETV6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ETV6 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Western blot testing of human 1) placenta, 2) HeLa, 3) 22RV1, 4) SKOV and 5) A549 lysate with ETV6 antibody at 0.5ug/ml. Predicted molecular weight ~53 kDa.

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