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PEA3 Antibody / ETV4

CAT: 0800-F54869-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F54869-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ETV4/PEA3 is a transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:500-1:1000
UniProt
P43268
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 419-447 from the human protein was used as the immunogen for the PEA3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IHC-P, WB
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PEA3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PEA3 antibody is available for research use only.
Storage Conditions
Aliquot the PEA3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the PEA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear
Image Legend
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with PEA3 antibody.

UniProtKB · P43268

ETS translocation variant 4

ETV4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P43268
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ETV4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K314, B7Z5J3, B7Z9J6, Q96AW9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Biological process

NeurogenesisTranscriptionTranscription regulation

Cellular component

Nucleus

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