ICOS Antibody

• Description :

  Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene. The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.

• CAS Number :

  9007-83-4

• Specifications :

  Western Blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

• UniProt :

  Q9WVS0

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A recombinant mouse partial protein corresponding to amino acids E21-S200 was used as the immunogen for the ICOS antibody.

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  WB, IHC-P, ELISA

• Purity :

  Antigen affinity purified

• Format :

  Antigen affinity purified

• Buffer :

  Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

• Reconstitution :

  After reconstitution, the ICOS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations :

  This ICOS antibody is available for research use only.

• Storage Conditions :

  After reconstitution, the ICOS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation :

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes :

  Optimal dilution of the ICOS antibody should be determined by the researcher.

• Location :

  Cytoplasmic, cell membrane

• Image Legend :

  Western blot testing of 1) mouse stomach, 2) mouse spleen, 3) mouse thymus, 4) mouse small intestine, 5) rat thymus and 6) human placental lysate with ICOS antibody at 0.5ug/ml. Predicted molecular weight ~23 kDa.