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HSP20 Antibody

CAT: 0800-R32978Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32978Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Heat shock protein beta-6 is a protein that in humans is encoded by the HSPB6 gene. HSPB6, also known as hsp20, is a 17-kDa member of the small heat shock family of proteins. It is expressed in multiple tissues; however, HSPB6 is most highly and constitutively expressed in different types of muscle including vascular, airway, colonic, bladder, uterine smooth muscle, cardiac muscle and skeletal muscle. HSPB6 has specific functions for vasodilation, platelet function, and insulin resistance and in smooth and cardiac muscle.
CAS Number
9007-83-4
Specifications
Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Immunofluorescence: 2-4 µg/mL
UniProt
O14558
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant human protein corresponding to amino acids H73-L123 was used as the immunogen for the HSP20 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the HSP20 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This HSP20 antibody is available for research use only.
Storage Conditions
After reconstitution, the HSP20 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the HSP20 antibody should be determined by the researcher.
Image Legend
Immunofluorescent staining of FFPE human A431 cells with HSP20 antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · O14558

Heat shock protein beta-6

HSPB6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14558
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HSPB6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
HspB6
EC number
—
Processing
—
Secondary accessions
O14551, Q6NVI3, Q96MG9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

Chaperone

Cellular component

CytoplasmNucleusSecreted

PTM

Phosphoprotein

Biological process

Stress response

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