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RANK Antibody

CAT: 0800-R32806Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32806Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Receptor Activator of Nuclear Factor kB (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. It is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, this gene is mapped to 18q22.1.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL
UniProt
Q9Y6Q6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 235-262 (YRKKGKALTANLWHWINEACGRLSGDKE) from the human protein were used as the immunogen for the RANK antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the RANK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RANK antibody is available for research use only.
Storage Conditions
After reconstitution, the RANK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the RANK antibody should be determined by the researcher.
Location
Cytoplasmic, membranous
Image Legend
IHC testing of FFPE human intestinal cancer tissue with RANK antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
Product Datasheet
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