HtrA3 Antibody

CAT: 0800-R32751Size: 100 µgDry Ice: NoHazardous: No

1 / 1

CAT#:0800-R32751Size:100 µg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Human HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. It may also have a role in ovarian development, granulosa cell differentiation and luteinization. The long isoform, HTRA3L, contains 453 amino acids and has a predicted molecular mass of 49 kD. It contains an N-terminal signal peptide, followed by an insulin/IGF (see 147440) -binding domain, a Kazal-type S protease inhibitor domain, a trypsin protease domain, and a PDZ domain. The short isoform, HTRA3S, contains 357 amino acids and has a predicted molecular mass of 38 kD.

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL

UniProt

P83110

Host

Rabbit

Reactivity

Human

Immunogen

Amino acids 330-362 (FAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMR) from the human protein were used as the immunogen for the HtrA3 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide

Reconstitution

After reconstitution, the HtrA3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This HtrA3 antibody is available for research use only.

Storage Conditions

After reconstitution, the HtrA3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the HtrA3 antibody should be determined by the researcher.

Image Legend

Western blot testing of human 1) PANC1 and 2) HepG2 cell lysate with HtrA3 antibody at 0.5ug/ml. Predicted molecular weight ~49 kDa.

UniProtKB · P83110

Serine protease HTRA3

HTRA3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P83110
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: HTRA3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.4.21.-
Processing: Precursor
Secondary accessions: Q7Z7A2

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bond

Molecular function

HydrolaseProteaseSerine protease

Cellular component

Secreted

Domain

Signal

Product Datasheet

Related Products

Catalog	Name
FY13087	HTRA1 Antibody / HtrA serine peptidase 1
F54502-0.05ML	HTRA1 Antibody
F54030-0.1ML	HtrA2 Antibody
RQ4736	HTRA2 Antibody
F54502-0.2ML	HTRA1 Antibody
F54031-0.1ML	HtrA2 Antibody
RQ4205	HTRA1 Antibody
FY13227	HTRA4 Antibody / Serine protease HTRA4
RQ8668	OMI Antibody / HTRA2
R34121-100UG	Serotonin Receptor 3A Antibody / HTR3A

Alternative Products

Catalog	Name
abx214625-01	Serine Protease HTRA3 (HTRA3) Antibody
MBS8590702-01	HTRA3 Antibody
MBS8569342-01	HTRA3 Polyclonal Antibody
CQA4733-01	Anti-HTRA3 Antibody
C37361	HTRA3 Conjugated Antibody
E45R31186G-4	HTRA3 Antibody (Center)
377412	HtrA3 (Serine Protease HTRA3)
319733-01	HTRA3
YP-W34518-01	Rat HTRA3 (HTRA3) ELISA Kit
YP-W16196-01	Human HTRA3 (HTRA3) ELISA Kit