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Vinculin Antibody

CAT: 0800-R32692Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32692Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P18206
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids E930-Q1134 from the human protein were used as the immunogen for the Vinculin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Vinculin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Vinculin antibody is available for research use only.
Storage Conditions
After reconstitution, the Vinculin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Vinculin antibody should be determined by the researcher.
Image Legend
Western blot testing of human A549 cell lysate with Vinculin antibody at 0.5ug/ml. Predicted molecular weight ~124 kDa.

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