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ADAR1 Antibody

CAT: 0800-R32461Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32461Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Double-stranded RNA-specific adenosine deaminase, also known as ADAR1, is an enzyme that in humans is encoded by the ADAR gene. It is mapped to 1q21.3. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL
UniProt
P55265
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids S128-Q346 from the human protein were used as the immunogen for the ADAR1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
Prior to reconstitution, store at 4oC. After reconstitution, the ADAR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ADAR1 antibody is available for research use only.
Storage Conditions
Prior to reconstitution, store at 4°C. After reconstitution, the ADAR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ADAR1 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Western blot testing of human 1) HeLa, 2) A549, 3) MCF7 and 4) HepG2 cell lysate with ADAR1 antibody at 0.5ug/ml. Expected molecular weight: 110-150 kDa.

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