ABL2 Antibody

CAT: 0800-R32426Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R32426Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tyrosine-protein kinase ABL2, also known as Abelson-related gene (Arg), is an enzyme that in humans is encoded by the ABL2 gene. This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL
Gene ID
27
UniProt
P42684
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids T1065-R1182 of the human protein were used as the immunogen for the ABL2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the ABL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ABL2 antibody is available for research use only.
Storage Conditions
After reconstitution, the ABL2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ABL2 antibody should be determined by the researcher.
Location
Cytoplasmic, membranous, nuclear
Image Legend
IHC testing of FFPE human gallbladder carcinoma tissue with ABL2 antibody. HEIR: Boil the paraffin sections in pH8 EDTA buffer for 20 minutes and allow to cool prior to testing.

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