Products for Research Use Only
RegisterLogin

C-Abl Antibody / ABL1

CAT: 0800-R31857Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31857Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
C-Abl is also called as ABL1. This gene is a proto-oncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t (9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene. Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
P00519
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids ERIASGAITKGVVLDSTEALCLAISRNSEQ of human ABL1 were used as the immunogen for the c-Abl antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the c-Abl antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This c-Abl antibody is available for research use only.
Storage Conditions
After reconstitution, the c-Abl antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the c-Abl antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat brain and 2) human HeLa lysate with c-Abl antibody. Expected molecular weight: routinely visualized at 123-150 kDa, observed here at ~150 kDa.

Related Products

CatalogName
F50696-0.08MLC-Abl Antibody
F50696-0.4MLC-Abl Antibody
F43352-0.4MLAbl1 Antibody
F50694-0.4MLABL1 Antibody
F43352-0.08MLAbl1 Antibody
F50695-0.08MLABL1 Antibody
F50695-0.4MLABL1 Antibody
F50694-0.08MLABL1 Antibody
R32426ABL2 Antibody
F53161-0.08MLABL2 Antibody

Alternative Products

CatalogName
GTR18224893ABL1/c-ABL Antibody
MBS2401903-01Anti-ABL1/c-ABL Antibody
GTR18785188-01C ABL (ABL1) Antibody (C-term)
M00133Anti-c-Abl ABL1 Monoclonal Antibody
AP20341PU-Nc Abl (ABL1) Rabbit Polyclonal Antibody
GTR17689095C Abl/ABL1 Rabbit Polyclonal Antibody
PB9468Anti-c Abl/ABL1 Antibody Picoband®
GTR18962685C ABL (ABL1) Antibody Blocking peptide
MBS6405083-01ABL1 (ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl) (HRP)
209334-01ABL1 (ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl) discontinued

Popular Products