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EPCR Antibody / CD201

CAT: 0800-R32352Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32352Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor), is a protein that in humans is encoded by the PROCR gene. It has also recently been designated CD201 (cluster of differentiation 201) . The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. And it is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, ELISA: 0.1-0.5 µg/mL (human protein tested) ; request BSA-free format for coating
UniProt
Q9UNN8
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 18-210 of human EPCR/CD201 were used as the immunogen for the EPCR antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA (protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the EPCR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This EPCR antibody is available for research use only.
Storage Conditions
After reconstitution, the EPCR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the EPCR antibody should be determined by the researcher.
Image Legend
Western blot testing of human A549 cell lysate with EPCR antibody. Expected molecular weight ~24/36-46 kDa (unmodified/glycosylated) . The ~52 kDa band may represent a further modification of the protein.

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