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TRPM5 Antibody

CAT: 0800-R32340Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32340Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a protein that in humans is encoded by the TRPM5 gene. This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca (2+) ions. It is activated by lower concentrations of intracellular Ca (2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL
UniProt
Q9NZQ8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 1021-1108 of human TRPM5 were used as the immunogen for the TRPM5 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the TRPM5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TRPM5 antibody is available for research use only.
Storage Conditions
After reconstitution, the TRPM5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TRPM5 antibody should be determined by the researcher.
Location
Cytoplasmic, membranous
Image Legend
Western blot testing of human 1) SMMC and 2) 293 cell lysate with TRPM5 antibody. Expected/observed molecular weight ~131 kDa.

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